Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996230 | 1.00 | KMT2A (0.39) | KMT2AMEN1DGKAVCAM1PTGS2 | |
| SCHEMBL3940182 | 1.00 | KMT2A (0.39) | KMT2AMEN1DGKAVCAM1PTGS2 | |
| SCHEMBL3537007 | 0.98 | KMT2A (0.40) | KMT2AMEN1DGKAVCAM1PTGS2 | |
| SCHEMBL3536100 | 0.92 | KMT2A (0.41) | KMT2AMEN1VCAM1LMNATSHR | |
| SCHEMBL25495837 | 0.92 | KMT2A (0.43) | KMT2AMEN1DGKAVCAM1LMNA | |
| SCHEMBL522462 | 0.92 | KMT2A (0.43) | KMT2AMEN1DGKAVCAM1LMNA | |
| SCHEMBL21049231 | 0.92 | KMT2A (0.43) | KMT2AMEN1DGKAVCAM1LMNA | |
| SCHEMBL4953772 | 0.90 | KMT2A (0.44) | KMT2AMEN1DGKAVCAM1LMNA | |
| SCHEMBL17337909 | 0.86 | KMT2A (0.48) | KMT2AMEN1DGKAVCAM1LMNA | |
| SCHEMBL7880107 | 0.85 | VCAM1 (0.43) | KMT2AMEN1DGKAVCAM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563151-A | PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0623116-A1 | AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014072-A1 | AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |