Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CCND3 | P30281 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996330 | 0.92 | AMY1A (0.54) | NPC1RAB9AAMY1AKMT2ADHODH | |
| SCHEMBL8996325 | 0.88 | F7 (0.51) | NPC1RAB9AKMT2AMEN1F7 | |
| SCHEMBL8996340 | 0.82 | KDM4E (0.54) | NPC1RAB9AAMY1AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8996365 | 0.81 | KDM4E (0.53) | NPC1RAB9AAMY1AKMT2AMEN1 | |
| SCHEMBL8996422 | 0.79 | KMT2A (0.50) | NPC1RAB9AAMY1AKMT2AMEN1 | |
| SCHEMBL24140790 | 0.76 | AMY1A (0.62) | NPC1RAB9AAMY1AKMT2ACYP1A1 | |
| SCHEMBL7395130 | 0.76 | AMY1A (0.69) | NPC1RAB9AAMY1AKMT2AUSP2 | |
| SCHEMBL31429770 | 0.75 | AMY1A (0.62) | NPC1RAB9AAMY1AKMT2AMEN1 | |
| SCHEMBL15456540 | 0.74 | CYP1A1 (0.69) | NPC1RAB9AAMY1AKMT2ACYP1A1 | |
| SCHEMBL8930315 | 0.72 | MAPT (0.73) | KMT2AMEN1EGFRPIM1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |