Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996336 | 0.92 | NPC1 (0.48) | AMY1ANPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8996340 | 0.85 | KDM4E (0.54) | AMY1ANPC1RAB9AKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8996365 | 0.84 | KDM4E (0.53) | AMY1ANPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8996422 | 0.82 | KMT2A (0.50) | AMY1ANPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8996325 | 0.78 | F7 (0.51) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8996320 | 0.76 | EGFR (0.45) | RAB9AKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7917574 | 0.75 | ALDH1A1 (0.61) | AMY1ANPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8996419 | 0.75 | ELANE (0.44) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7395130 | 0.74 | AMY1A (0.69) | AMY1ANPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL2314062 | 0.74 | NPC1 (0.57) | AMY1ANPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |