Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | RECQL | P46063 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996324 | 0.85 | FTO (0.68) | FTOTHRBMEN1KMT2AKDM4E | |
| SCHEMBL8996447 | 0.84 | MAPT (0.66) | FTOTHRBMEN1KMT2AKDM4E | |
| SCHEMBL7158879 | 0.79 | SELL (0.52) | FTOTHRBMEN1KMT2AKDM4E | |
| SCHEMBL3275730 | 0.77 | MAPT (0.67) | THRBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL7160699 | 0.76 | MEN1 (0.54) | FTOTHRBMEN1KMT2AKDM4E | |
| SCHEMBL9173749 | 0.74 | MAPT (0.61) | THRBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL3192484 | 0.73 | CSNK2A2 (0.70) | THRBMEN1KMT2AKDM4EMAPT | |
| Cynodontin SCHEMBL31310659 | 0.72 | MAPT (0.88) | THRBMEN1KMT2AKDM4EMAPT | |
| Cynodontin SCHEMBL9172388 | 0.72 | MAPT (0.88) | THRBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL23896699 | 0.72 | CSNK2A2 (0.56) | FTOTHRBMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | claimed |
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| CN-1079732-A | Medical compounds | LILLY INDUSTRIES LTD (GB) | 1993-12-22 | — | — | CN | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |