SCHEMBL8996621

SCHEMBL8996621

N#Cc1c(OC(F)F)nsc1SC1CCCC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.32
MAOB P27338 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9412192 0.99 MAOA (0.34) MAOAMAOB
SCHEMBL8996607 0.78 ALDH1A1 (0.40)
SCHEMBL9412196 0.76 ALDH1A1 (0.36) MAOAMAOB
SCHEMBL9412224 0.75 FNTA (0.33)
SCHEMBL9412324 0.75 ALDH1A1 (0.36) MAOAMAOB
SCHEMBL9412288 0.75 MAOA (0.36) MAOAMAOB
SCHEMBL9412251 0.74 ALDH1A1 (0.31)
SCHEMBL9412204 0.73 ALDH1A1 (0.39)
SCHEMBL9412190 0.72 MAPT (0.39)
SCHEMBL9412274 0.72 MAPT (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484934-A FUNGICIDE, WOOD PRESERVATIVE NIHON NOHYAKU CO., LTD. (JP) 1996-01-16 US disclosed
EP-0604978-A1 Isothiazole derivatives, a process for production thereof and uses thereof NIHON NOHYAKU CO., LTD. (JP) 1994-07-06 EP disclosed
EP-0578246-A1 Isothiazole derivatives and processes for preparing the same as well as termite controlling agents comprising the same as active ingredient NIHON NOHYAKU CO., LTD. (JP) 1994-01-12 EP disclosed