Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996605 | 0.77 | MAOA (0.41) | MAPTGAAALPGKMT2AMEN1 | |
| SCHEMBL9412193 | 0.77 | MAPT (0.49) | MAPTGAAALPGHIF1AKMT2A | |
| SCHEMBL9412310 | 0.73 | ALDH1A1 (0.45) | MAPTGAAALPGHIF1AKMT2A | |
| SCHEMBL10332462 | 0.73 | ALDH1A1 (0.52) | MAPTGAAALPGHIF1AKMT2A | |
| SCHEMBL9412305 | 0.71 | MAOB (0.44) | MAPTGAAALPGHIF1AALDH1A1 | |
| SCHEMBL21917572 | 0.71 | ALDH1A1 (0.52) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL10332463 | 0.70 | ALDH1A1 (0.59) | MAPTGAAALPGHIF1AKMT2A | |
| SCHEMBL5941105 | 0.70 | HTT (0.53) | MAPTGAAALPGKMT2AMEN1 | |
| SCHEMBL11561226 | 0.69 | ALDH1A1 (0.36) | MAPTGAAALPGKMT2AMEN1 | |
| SCHEMBL9332731 | 0.69 | ALDH1A1 (0.36) | MAPTGAAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484934-A | FUNGICIDE, WOOD PRESERVATIVE | NIHON NOHYAKU CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0604978-A1 | Isothiazole derivatives, a process for production thereof and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |