SCHEMBL8996680

SCHEMBL8996680

CC(C)(CC1CCCCC1)C1(C)OCC(CC2CCCCCN2)O1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.30
CYP2D6 P10635 2/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
TSHR P16473 1/20 0.30
KMT2A Q03164 1/20 0.30
MLNR O43193 1/20 0.30
ABCB11 O95342 1/20 0.30
EGFR P00533 1/20 0.30
FYN P06241 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
HTR1A P08908 1/20 0.30
CHRM5 P08912 1/20 0.30
ADRA2A P08913 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
CHRM1 P11229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9003936 0.80
SCHEMBL8996578 0.73 ADRA2C (0.40) HTR1ACHRM5ADRA2AADRA2BADRA2C
SCHEMBL8996683 0.73 ADRA2C (0.40) HTR1ACHRM5ADRA2AADRA2BADRA2C
SCHEMBL3357476 0.67 CYP2D6 (0.46) FDPSCYP2D6MEN1ALDH1A1LMNA
SCHEMBL9734909 0.65
SCHEMBL28881650 0.65 CYP2D6 (0.42) FDPSCYP2D6MEN1ALDH1A1LMNA
SCHEMBL23585075 0.65 CYP2D6 (0.50) FDPSCYP2D6MEN1ALDH1A1LMNA
SCHEMBL10955098 0.65 CYP2D6 (0.50) FDPSCYP2D6MEN1ALDH1A1LMNA
SCHEMBL25834098 0.65 CYP2D6 (0.50) FDPSCYP2D6MEN1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL11189926 0.63 KMT2A (0.48) FDPSCYP2D6MEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5571930-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-11-05 US disclosed
US-5493034-A Intermediate for pesticidal aminomethylheterocyclic compounds BAYER AKTIENGESELLSCHAFT (DE) 1996-02-20 US disclosed
US-5447927-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1995-09-05 US disclosed
US-5376660-A An aminomethyl-1,4-dioxaspiro(4,5)decanes pesticides or fungicides BAYER AKTIENGESELLSCHAFT (DE) 1994-12-27 US disclosed
EP-0355597-B1 SUBSTITUTED DIOXOLANYLETHYLAMINES, PROCESS FOR THEIR PREPARATION, THEIR USE IN PESTICIDES, AND INTERMEDIATES BAYER AG (DE) 1993-06-09 EP disclosed
US-5177103-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1993-01-05 US disclosed
EP-0359979-B1 AMINOMETHYLHETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION, THEIR USE IN PESTICIDES, AND INTERMEDIATES BAYER AG (DE) 1992-12-30 EP disclosed
US-5010101-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed
US-4985421-A Fungicidal substituted dioxolanylethylamine BAYER AKTIENGESELLSCHAFT (DE) 1991-01-15 US disclosed
EP-0359979-A1 Aminomethylheterocyclic compounds, process for their preparation, their use in pesticides, and intermediates BAYER AG (DE) 1990-03-28 EP disclosed
EP-0355597-A1 Substituted dioxolanylethylamines, process for their preparation, their use in pesticides, and intermediates BAYER AG (DE) 1990-02-28 EP disclosed