Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996683 | 1.00 | ADRA2C (0.40) | ADRA2CCHRM5GAAHTR1ATMEM97 | |
| SCHEMBL9003942 | 0.78 | GAA (0.37) | ADRA2CCHRM5GAAHTR1ATMEM97 | |
| SCHEMBL8996680 | 0.73 | FDPS (0.30) | ADRA2CCHRM5HTR1ASIGMAR1ADRA2A | |
| SCHEMBL11005987 | 0.72 | HRH3 (0.40) | TMEM97SIGMAR1 | |
| SCHEMBL10569249 | 0.71 | TDP1 (0.43) | HTR1ATMEM97SIGMAR1ADRA1AADRA1B | |
| SCHEMBL8996583 | 0.69 | CHRM5 (0.38) | ADRA2CCHRM5GAAHTR1ATMEM97 | |
| SCHEMBL9734909 | 0.68 | — | — | |
| SCHEMBL10487078 | 0.68 | GAA (0.56) | GAAHTR1ATMEM97SIGMAR1ADRA1A | |
| SCHEMBL10487109 | 0.68 | GAA (0.56) | GAAHTR1ATMEM97SIGMAR1ADRA1A | |
| SCHEMBL11005989 | 0.67 | HRH4 (0.39) | ADRA2CHTR1ATMEM97SIGMAR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571930-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |
| US-5493034-A | Intermediate for pesticidal aminomethylheterocyclic compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-20 | — | — | US | disclosed |
| US-5447927-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-05 | — | — | US | disclosed |
| US-5376660-A | An aminomethyl-1,4-dioxaspiro(4,5)decanes pesticides or fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-27 | — | — | US | disclosed |
| EP-0355597-B1 | SUBSTITUTED DIOXOLANYLETHYLAMINES, PROCESS FOR THEIR PREPARATION, THEIR USE IN PESTICIDES, AND INTERMEDIATES | BAYER AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-5177103-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-05 | — | — | US | disclosed |
| EP-0359979-B1 | AMINOMETHYLHETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION, THEIR USE IN PESTICIDES, AND INTERMEDIATES | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| US-5010101-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| US-4985421-A | Fungicidal substituted dioxolanylethylamine | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0359979-A1 | Aminomethylheterocyclic compounds, process for their preparation, their use in pesticides, and intermediates | BAYER AG (DE) | 1990-03-28 | — | — | EP | disclosed |
| EP-0355597-A1 | Substituted dioxolanylethylamines, process for their preparation, their use in pesticides, and intermediates | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |