SCHEMBL8996894

SCHEMBL8996894

CCCCOc1c(C(=O)OCC)cc(C)c(N)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
LMNA P02545 3/20 0.44
ALDH1A1 P00352 7/20 0.43
L3MBTL1 Q9Y468 3/20 0.42
TSHR P16473 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
ESR1 P03372 1/20 0.41
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.40
HSP90AA1 P07900 1/20 0.40
KDM4E B2RXH2 3/20 0.39
POLB P06746 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28541481 0.86 CNR2 (0.45) NPC1RAB9AALDH1A1L3MBTL1TSHR
SCHEMBL8134965 0.82 ALDH1A1 (0.55) HSD17B10NPC1RAB9ALMNAALDH1A1
SCHEMBL14975102 0.78 TSHR (0.45) HSD17B10NPC1RAB9ALMNAALDH1A1
SCHEMBL4627305 0.76 TSHR (0.61) HSD17B10LMNAALDH1A1L3MBTL1TSHR
SCHEMBL13367226 0.75 KDM4E (0.56) HSD17B10NPC1LMNAALDH1A1L3MBTL1
SCHEMBL7928303 0.75 ESR1 (0.54) HSD17B10NPC1RAB9ALMNATSHR
SCHEMBL14975083 0.74 TSHR (0.44) HSD17B10NPC1RAB9ALMNAALDH1A1
SCHEMBL4626575 0.74 TSHR (0.54) HSD17B10LMNAALDH1A1L3MBTL1TSHR
SCHEMBL4626438 0.74 TSHR (0.54) HSD17B10LMNAALDH1A1L3MBTL1TSHR
SCHEMBL14975472 0.73 THRA (0.48) HSD17B10LMNAALDH1A1TSHRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0402546-B1 Printed circuit board POLY FLEX CIRCUITS INC (US) 1996-09-04 EP disclosed
US-5180513-A Silver coated magnetite particles dispersed in cycloaliphatic epoxy resin KEY-TECH, INC. (US) 1993-01-19 US disclosed
US-5093038-A ULTRAVIOLET CURABLE INK COMPOSITION KEY-TECH, INC. (US) 1992-03-03 US disclosed
US-5047260-A Curing by UV radiation an interior coating of silver-coated magnetite particles suspended in a polymer KEY-TECH, INC. (US) 1991-09-10 US disclosed
US-5036128-A UV curable ink containing thermosetting resin binder, ketone-amine curing agent, electroconductive particles KEY-TECH, INC. (US) 1991-07-30 US disclosed
US-5006397-A Using ultraviolet curable ink KEY-TECH, INC. (US) 1991-04-09 US disclosed
EP-0402546-A2 Printed circuit board POLY-FLEX CIRCUITS, INC. (US) 1990-12-19 EP disclosed
US-4960614-A UV RAD CURING OF PRINTED INK IN PULSING MANNER, NON-EXPOSURE PERIODS KEY-TECH, INC. (US) 1990-10-02 US disclosed