Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299856 | 0.69 | ALDH1A1 (0.46) | HSD17B10POLBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5528668 | 0.68 | MEN1 (0.66) | POLBALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL22537714 | 0.67 | TSHR (0.71) | ABCB1POLBCYP19A1CYP1A2CYP2D6 | |
| SCHEMBL99122 | 0.67 | CYP11B1 (0.50) | POLBCYP19A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5728469 | 0.66 | HRH1 (0.43) | CYP19A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9276184 | 0.65 | SLC6A2 (0.37) | — | |
| SCHEMBL492258 | 0.65 | TSHR (0.52) | ABCB1HSD17B10LOXL2CYP19A1ALDH1A1 | |
| SCHEMBL5789318 | 0.64 | ALDH1A1 (0.55) | ABCB1IKBKBHSD17B10POLBALDH1A1 | |
| SCHEMBL4569962 | 0.64 | F2 (0.60) | ABCB1IKBKBPOLBCYP19A1ALDH1A1 | |
| SCHEMBL8310756 | 0.64 | CYP1A2 (0.50) | HRH4LOXL2CYP19A1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489595-A | TREATING RHEUMATOID ARTHRITIS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-02-06 | — | — | US | disclosed |