SCHEMBL99122

SCHEMBL99122

c1ccc(COn2ccnc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.50
CYP11B2 P19099 4/20 0.50
CYP19A1 P11511 3/20 0.50
CYP3A4 P08684 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2D6 P10635 2/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
TBXAS1 P24557 1/20 0.50
QPCT Q16769 1/20 0.50
CYP4Z1 Q86W10 1/20 0.50
QPCTL Q9NXS2 1/20 0.50
HMOX1 P09601 1/20 0.47
TDP1 Q9NUW8 1/20 0.42
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
CYP2C19 P33261 1/20 0.41
CYP17A1 P05093 1/20 0.41
LTA4H P09960 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL8917652 0.95 CYP11B1 (0.49) CYP11B1CYP11B2CYP19A1CYP3A4CYP1A2
SCHEMBL3168682 0.84 CYP11B1 (0.54) CYP11B1CYP11B2CYP19A1CYP3A4CYP1A2
SCHEMBL11013739 0.82 TDP1 (0.47) CYP11B1CYP11B2CYP19A1CYP3A4CYP1A2
SCHEMBL28179425 0.80 TDP1 (0.53) CYP11B1CYP11B2CYP19A1CYP3A4CYP1A2
SCHEMBL8497604 0.79 CYP19A1 (0.45) CYP11B1CYP11B2CYP19A1POLBTDP1
SCHEMBL21104644 0.78 CYP11B1 (0.44) CYP11B1CYP11B2CYP19A1CYP3A4CYP1A2
SCHEMBL27792150 0.76 TSHR (0.50) CYP1A2TDP1ALOX15CYP2C19
SCHEMBL12682673 0.75 IDO1 (0.46) CYP11B1CYP11B2CYP19A1CYP2D6MAPT
SCHEMBL17315100 0.75 CYP19A1 (0.46) CYP11B1CYP11B2CYP19A1CYP3A4CYP1A2
SCHEMBL5650539 0.75 RAB9A (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110997742-B Polymer composition comprising a fluorescent dye, method for the production thereof, use thereof and objects comprising the same 埃尼股份公司 2022-09-27 CN claimed
CN-110997742-A Polymer composition comprising a fluorescent dye, method for the production thereof, use thereof and objects comprising the same 埃尼股份公司 2020-04-10 CN claimed
US-10125226-B2 Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2018-11-13 US claimed
US-20140364566-A1 SCALE-UP PROCESS OF BIFUNCTIONALIZED TRIBLOCK COPOLYMERS WITH SECONDARY AND TERTIARY AMINES, WITH APPLICATION IN DEWATERING AND DESALTING OF HEAVY CRUDE OILS INSTITUTO MEXICANO DEL PETROLEO (MX) 2014-12-11 US claimed
CN-110997742-B Polymer composition comprising a fluorescent dye, method for the production thereof, use thereof and objects comprising the same 埃尼股份公司 2022-09-27 CN disclosed
CN-110997742-A Polymer composition comprising a fluorescent dye, method for the production thereof, use thereof and objects comprising the same 埃尼股份公司 2020-04-10 CN disclosed
US-10167388-B2 Block copolymers, synthesis and application as dehydrating and desalting of heavy crudes INSTITUTO MEXICANO DEL PETROLEO (MX) 2019-01-01 US disclosed
EP-2430029-B1 THIENO[2,3-B]PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS UNIV LEUVEN KATH (BE) 2018-01-10 EP disclosed
US-20170327686-A1 BLOCK COPOLYMERS, SYNTHESIS AND APPLICATION AS DEHYDRATING AND DESALTING OF HEAVY CRUDES MEXICANO INST PETROL (MX) 2017-11-16 US disclosed
US-9752084-B2 Block copolymers, synthesis and application as dehydrating and desalting of heavy crudes INSTITUTO MEXICANO DEL PETROLEO (MX) 2017-09-05 US disclosed
US-9499563-B2 Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2016-11-22 US disclosed
US-9499563-B2 Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2016-11-22 US disclosed
CN-101330916-A Substituted imidazoquinolines, imidazonaphthyridines, and imidazopyridines, compositions, and methods thereof COLEY PHARMACEUTICAL INC (US) 2008-12-24 CN disclosed
WO-2008006824-A1 NOVEL TYROSINASE INHIBITORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN HUMAN MEDICINE AND IN COSMETICS GALDERMA RESEARCH & DEVELOPMENT (FR) 2008-01-17 WO disclosed
CN-101010060-A Keratin dyeing compounds, keratin dyeing compositions containing them and their use PROCTER & GAMBLE (US) 2007-08-01 CN disclosed
WO-2007039821-A2 NOVEL INHIBITORS OF TYROSINASE, THEIR METHOD OF PREPARATION AND THEIR USE IN HUMAN MEDICINE AND IN COSMETICS GALDERMA RESEARCH & DEVELOPMENT (FR) 2007-04-12 WO disclosed
CN-1922178-A Piperazine, [1,4] diazepane , [1,4] diazacyclooctane ([1,4] diazocane), and [1,5] diazacyclooctane ([1,5] diazocane) fused imidazo ring compounds 3M INNOVATIVE PROPERTIES CO (US) 2007-02-28 CN disclosed
CN-1897948-A Alkoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES CO (US) 2007-01-17 CN disclosed
CN-1842336-A Aryloxy and arylalkyleneoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES CO (US) 2006-10-04 CN disclosed
CN-1784231-A 1-amino 1H-imidazoquinolines 3M INNOVATIVE PROPERTIES CO (US) 2006-06-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10167388-B2 Block copolymers, synthesis and application as dehydrating and desalting of heavy crudes DEGS1, AQP1, AQP3 CYP11B1 1229/4885CYP11B2 1409/4885CYP19A1 1407/4885
US-20170327686-A1 BLOCK COPOLYMERS, SYNTHESIS AND APPLICATION AS DEHYDRATING AND DESALTING OF HEAVY CRUDES DEGS1, AQP1, AQP3 CYP11B1 1229/4885CYP11B2 1409/4885CYP19A1 1407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.