Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1957930 | 0.93 | LMNA (0.65) | LMNAMAPK1HIF1ASRCESR1 | |
| SCHEMBL352555 | 0.93 | LMNA (0.65) | LMNAMAPK1HIF1ASRCESR1 | |
| SCHEMBL467741 | 0.93 | LMNA (0.65) | LMNAMAPK1HIF1ASRCESR1 | |
| SCHEMBL31484031 | 0.93 | LMNA (0.65) | LMNAMAPK1HIF1ASRCESR1 | |
| SCHEMBL7522519 | 0.91 | LMNA (0.62) | LMNAMAPK1HIF1ASRCESR1 | |
| Water SCHEMBL564812 | 0.91 | LMNA (0.62) | LMNAMAPK1HIF1ASRCESR1 | |
| SCHEMBL10954019 | 0.91 | LMNA (0.62) | LMNAMAPK1HIF1ASRCESR1 | |
| SCHEMBL10957256 | 0.91 | LMNA (0.62) | LMNAMAPK1HIF1ASRCESR1 | |
| SCHEMBL5088395 | 0.91 | LMNA (0.62) | LMNAMAPK1HIF1ASRCESR1 | |
| Ammonia Solution, Strong SCHEMBL7530577 | 0.91 | LMNA (0.62) | LMNAMAPK1HIF1ASRCESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459455-B1 | Process for producing optically active alpha-hydroxyesters | CHISSO CORP (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5248610-A | Transesterification | CHISSO CORPORATION (JP) | 1993-09-28 | — | — | US | disclosed |
| EP-0459455-A2 | Process for producing optically active alpha-hydroxyesters | CHISSO CORPORATION (JP) | 1991-12-04 | — | — | EP | disclosed |
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |