Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 5/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.44 |
| ▸ | FEN1 | P39748 | 7/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240985 | 0.86 | CASP1 (0.56) | CASP1MMP1MMP2MMP9MMP13 | |
| SCHEMBL8997264 | 0.84 | MCL1 (0.47) | KAT6ACASP1GAA | |
| SCHEMBL8997298 | 0.82 | NAT1 (0.50) | KAT6ACASP1 | |
| SCHEMBL3831543 | 0.81 | ALOX5AP (0.60) | ALOX5APFEN1 | |
| SCHEMBL778996 | 0.80 | PTPN1 (0.46) | KAT6AHTTALOX5APFEN1F10 | |
| Trifluoroacetic Acid SCHEMBL15924594 | 0.78 | FEN1 (0.54) | ALOX5APFEN1F10 | |
| SCHEMBL2566974 | 0.76 | ALOX5AP (0.56) | ALOX5APFEN1F10 | |
| SCHEMBL3836209 | 0.76 | ALOX5AP (0.48) | ALOX5APFEN1 | |
| SCHEMBL15924982 | 0.75 | FEN1 (0.62) | ALOX5APFEN1 | |
| SCHEMBL27176171 | 0.74 | KAT6A (0.58) | KAT6AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512681-A | HORMONE INHIBITORS FOR TREATMENT OF HYPERTENSION OR CONGESTIVE HEART FAILURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |