Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 3/20 | 0.43 |
| ▸ | EDNRA | P25101 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240985 | 0.87 | CASP1 (0.56) | MCL1CASP1EDNRBEDNRAMEN1 | |
| SCHEMBL8997298 | 0.84 | NAT1 (0.50) | MCL1NAMPTCASP1EDNRBEDNRA | |
| SCHEMBL8997316 | 0.84 | KAT6A (0.47) | CASP1KAT6AGAA | |
| SCHEMBL3884580 | 0.81 | CNR2 (0.44) | MCL1CNR2NAMPTL3MBTL1CNR1 | |
| SCHEMBL5681328 | 0.78 | CASP1 (0.78) | MCL1NAMPTCASP1L3MBTL1 | |
| SCHEMBL19475077 | 0.78 | ALOX5AP (0.46) | CNR2NAMPTCNR1ALDH1A1MAPT | |
| SCHEMBL5679414 | 0.78 | NPC1 (0.44) | CNR2NAMPTL3MBTL1CNR1ALDH1A1 | |
| SCHEMBL5147607 | 0.78 | CASP1 (0.54) | CASP1EDNRBEDNRAKDM4ETDP1 | |
| SCHEMBL29894177 | 0.77 | NAMPT (0.41) | NAMPTEDNRBEDNRAALDH1A1KMT2A | |
| Biphenyl SCHEMBL9178383 | 0.76 | SLC1A3 (0.51) | L3MBTL1POLBALDH1A1HPGDKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512681-A | HORMONE INHIBITORS FOR TREATMENT OF HYPERTENSION OR CONGESTIVE HEART FAILURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |