Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775940 | 0.84 | ACHE (0.33) | CRBN | |
| SCHEMBL9409027 | 0.77 | ACHE (0.33) | — | |
| Hydrochloric Acid SCHEMBL9266364 | 0.76 | ACHE (0.32) | — | |
| SCHEMBL21083952 | 0.74 | CRBN (0.32) | CRBN | |
| SCHEMBL9263485 | 0.73 | ACHE (0.39) | AGTR1 | |
| Hydrochloric Acid SCHEMBL21083524 | 0.73 | CRBN (0.31) | CRBN | |
| SCHEMBL21083856 | 0.71 | KMT2A (0.32) | — | |
| Hydrochloric Acid SCHEMBL21083939 | 0.70 | KMT2A (0.31) | — | |
| SCHEMBL13539597 | 0.69 | CNR1 (0.34) | — | |
| SCHEMBL9542233 | 0.69 | CALCRL (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512681-A | HORMONE INHIBITORS FOR TREATMENT OF HYPERTENSION OR CONGESTIVE HEART FAILURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0601039-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |
| WO-1993004046-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |