SCHEMBL9542233

SCHEMBL9542233

CCCC1=NC2(CCCC2)C(=O)N1.COC(=O)C1(N)CCCC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CALCRL Q16602 1/20 0.31
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4775940 0.82 ACHE (0.33) CALCRL
Hydrochloric Acid SCHEMBL535435 0.72 ACHE (0.39)
SCHEMBL4772835 0.72 PDE7B (0.35)
SCHEMBL9263485 0.72 ACHE (0.39)
SCHEMBL331908 0.71 NPSR1 (0.50)
SCHEMBL13539597 0.70 CNR1 (0.34)
SCHEMBL8997336 0.69 AGTR1 (0.34)
SCHEMBL240008 0.69 NPSR1 (0.48)
SCHEMBL1772581 0.69 NPSR1 (0.48)
SCHEMBL1809800 0.69 NPSR1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993004046-A1 ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-04 WO disclosed