Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GLS | O94925 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512534 | 1.00 | ALDH1A1 (0.64) | ALDH1A1CYP3A4KMT2ATSHRHSD17B10 | |
| SCHEMBL7512529 | 1.00 | ALDH1A1 (0.64) | ALDH1A1CYP3A4KMT2ATSHRHSD17B10 | |
| SCHEMBL7701655 | 0.87 | KMT2A (0.60) | ALDH1A1CYP3A4KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL7701652 | 0.87 | KMT2A (0.60) | ALDH1A1CYP3A4KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL19107067 | 0.84 | ALDH1A1 (0.62) | ALDH1A1CYP3A4KMT2ATSHRHSD17B10 | |
| SCHEMBL22356140 | 0.84 | KMT2A (0.56) | ALDH1A1CYP3A4KMT2ASMN1; SMN2KLK7 | |
| SCHEMBL22355972 | 0.84 | KMT2A (0.56) | ALDH1A1CYP3A4KMT2ASMN1; SMN2KLK7 | |
| SCHEMBL10984043 | 0.83 | KMT2A (0.51) | ALDH1A1CYP3A4KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL28731164 | 0.83 | KMT2A (0.51) | ALDH1A1CYP3A4KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL1286155 | 0.82 | ALDH1A1 (0.70) | ALDH1A1CYP3A4KMT2ATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459455-B1 | Process for producing optically active alpha-hydroxyesters | CHISSO CORP (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5248610-A | Transesterification | CHISSO CORPORATION (JP) | 1993-09-28 | — | — | US | disclosed |
| EP-0459455-A2 | Process for producing optically active alpha-hydroxyesters | CHISSO CORPORATION (JP) | 1991-12-04 | — | — | EP | disclosed |