Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701652 | 0.89 | KMT2A (0.60) | KMT2AALDH1A1CYP3A4KLK7PPARA | |
| SCHEMBL7512534 | 0.87 | ALDH1A1 (0.64) | KMT2AALDH1A1CYP3A4KLK7MEN1 | |
| SCHEMBL7512529 | 0.87 | ALDH1A1 (0.64) | KMT2AALDH1A1CYP3A4KLK7MEN1 | |
| SCHEMBL8997426 | 0.87 | ALDH1A1 (0.64) | KMT2AALDH1A1CYP3A4KLK7MEN1 | |
| SCHEMBL18207181 | 0.87 | KMT2A (0.50) | KMT2AALDH1A1CYP3A4KLK7PPARA | |
| SCHEMBL22355962 | 0.87 | KMT2A (0.50) | KMT2AALDH1A1CYP3A4KLK7PPARA | |
| SCHEMBL18206264 | 0.87 | KMT2A (0.50) | KMT2AALDH1A1CYP3A4KLK7PPARA | |
| SCHEMBL22356129 | 0.87 | KMT2A (0.50) | KMT2AALDH1A1CYP3A4KLK7PPARA | |
| SCHEMBL18206262 | 0.87 | KMT2A (0.50) | KMT2AALDH1A1CYP3A4KLK7PPARA | |
| SCHEMBL7704690 | 0.85 | ALDH1A1 (0.49) | KMT2AALDH1A1CYP3A4MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469193-B1 | THREE COMPONENT COUPLINGS OF ALIPHATIC ALCOHOLS, ALKYL HALIDES AND CARBON DIOXIDE IN THE PRESENCE OF CESIUM CARBONATE AND TETRABUTYLAMMONIUM IODIDE | UNIVERSITY OF SOUTH FLORIDA | 2002-10-22 | — | — | US | disclosed |
| WO-2000050376-A9 | EFFICIENT SYNTHESIS OF ALKYL CARBONATES | UNIV SOUTH FLORIDA (US) | 2001-10-11 | — | — | WO | disclosed |
| WO-2000050376-A2 | EFFICIENT SYNTHESIS OF ALKYL CARBONATES | UNIVERSITY OF SOUTH FLORIDA (US) | 2000-08-31 | — | — | WO | disclosed |