Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997524 | 0.87 | NOTUM (0.46) | L3MBTL1TSHRNOTUMKMT2A | |
| SCHEMBL9120515 | 0.86 | NPSR1 (0.62) | L3MBTL1NPSR1KDM4EHPGDTSHR | |
| SCHEMBL8984913 | 0.84 | L3MBTL1 (0.40) | L3MBTL1KDM4EATMTSHRNOTUM | |
| SCHEMBL8440699 | 0.82 | NPSR1 (0.57) | L3MBTL1NPSR1KDM4EHPGDTSHR | |
| SCHEMBL9122127 | 0.81 | KDM4E (0.62) | NPSR1KDM4EHPGDATMTSHR | |
| SCHEMBL8158392 | 0.79 | NOTUM (0.42) | L3MBTL1NPSR1KDM4EHPGDATM | |
| SCHEMBL8136081 | 0.79 | NOTUM (0.42) | L3MBTL1NPSR1KDM4EHPGDATM | |
| SCHEMBL9121090 | 0.78 | TSHR (0.48) | NPSR1KDM4EHPGDATMTSHR | |
| SCHEMBL9120303 | 0.77 | TSHR (0.52) | NPSR1KDM4EHPGDATMTSHR | |
| SCHEMBL9118209 | 0.76 | KDM4E (0.56) | NPSR1KDM4EHPGDATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6179654-A | — | — | None | — | — | JP | disclosed |
| US-5559139-A | ANTIISCHEMIC AGENTS, MICROCIRCULATION | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |
| US-5559139-A | ANTIISCHEMIC AGENTS, MICROCIRCULATION | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |
| JP-H06179654-A | 1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTER | BAYER AG | 1994-06-28 | — | — | JP | disclosed |