Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.46 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.39 |
| ▸ | S100A10 | P60903 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997531 | 0.87 | L3MBTL1 (0.48) | NOTUMKMT2ATSHRL3MBTL1 | |
| SCHEMBL8984913 | 0.80 | L3MBTL1 (0.40) | NOTUMANXA2S100A10KMT2ATSHR | |
| SCHEMBL8136081 | 0.74 | NOTUM (0.42) | NOTUMCCR2KMT2AP2RX7L3MBTL1 | |
| SCHEMBL9120515 | 0.72 | NPSR1 (0.62) | NOTUMTSHRL3MBTL1 | |
| SCHEMBL8322567 | 0.70 | KDR (0.38) | NOTUMKMT2AP2RX7TSHR | |
| SCHEMBL26970371 | 0.69 | HTR3E (0.42) | NOTUMCCR2 | |
| SCHEMBL8440699 | 0.69 | NPSR1 (0.57) | NOTUMTSHRL3MBTL1 | |
| SCHEMBL8602097 | 0.68 | DHODH (0.40) | NOTUMKMT2A | |
| SCHEMBL9364046 | 0.68 | NPSR1 (0.41) | NOTUMANXA2S100A10P2RX7TSHR | |
| SCHEMBL8158392 | 0.68 | NOTUM (0.42) | NOTUMKMT2AP2RX7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559139-A | ANTIISCHEMIC AGENTS, MICROCIRCULATION | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | claimed |
| US-5559139-A | ANTIISCHEMIC AGENTS, MICROCIRCULATION | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |