SCHEMBL8997540

SCHEMBL8997540

O=C1NC(=O)C(=C2NC(=S)NC2=O)N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
OGT O15294 1/20 0.41
USP2 O75604 1/20 0.41
MAPT P10636 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
METAP1 P53582 1/20 0.31
PRKD3 O94806 1/20 0.30
PRKCG P05129 1/20 0.30
PRKCB P05771 1/20 0.30
PRKCA P17252 1/20 0.30
PRKCH P24723 1/20 0.30
PRKCI P41743 1/20 0.30
PRKCE Q02156 1/20 0.30
PRKCQ Q04759 1/20 0.30
PRKCZ Q05513 1/20 0.30
PRKCD Q05655 1/20 0.30
PRKD1 Q15139 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5483954 0.73
SCHEMBL5807413 0.69 POLB (0.39) KDM4EOGTUSP2MAPTRECQL
SCHEMBL8997515 0.68 KDM4E (0.41) KDM4EOGTUSP2MAPTRECQL
SCHEMBL123424 0.65
SCHEMBL3037255 0.65
SCHEMBL11937036 0.63 POLB (0.39) MAPTPOLBGAAMETAP1
SCHEMBL5807409 0.63 POLB (0.39) MAPTPOLBGAAMETAP1
SCHEMBL6616749 0.61
SCHEMBL17714494 0.61 SIRT2 (0.48) POLBGAAMETAP1
Barbituric Acid SCHEMBL4726594 0.59 ALDH1A1 (0.44) KDM4EOGTUSP2MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0635756-A2 Thermal developing photosensitive member and image forming method using the thermal developing photosensitive member CANON KABUSHIKI KAISHA (JP) 1995-01-25 EP claimed
US-5482814-A Thermal developing photosensitive member and image forming method using the thermal developing photosensitive member CANON KABUSHIKI KAISHA (JP) 1996-01-09 US disclosed
EP-0635756-A2 Thermal developing photosensitive member and image forming method using the thermal developing photosensitive member CANON KABUSHIKI KAISHA (JP) 1995-01-25 EP disclosed