Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8997513 | 0.70 | ALDH1A1 (0.34) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10750531 | 0.69 | — | — | |
| SCHEMBL7154647 | 0.67 | — | — | |
| SCHEMBL9278545 | 0.67 | — | — | |
| Bromide SCHEMBL8997509 | 0.66 | TSHR (0.34) | TSHRALDH1A1SMN1; SMN2MAPTFAAH | |
| SCHEMBL14971234 | 0.64 | KDM4E (0.36) | TSHRALDH1A1SMN1; SMN2MAPTFAAH | |
| SCHEMBL15068247 | 0.64 | TSHR (0.43) | TSHRALDH1A1SMN1; SMN2MAPTFAAH | |
| SCHEMBL29510 | 0.64 | — | — | |
| Bromide SCHEMBL8997567 | 0.63 | ALDH1A1 (0.38) | TSHRALDH1A1 | |
| Dimethylamine SCHEMBL3468998 | 0.63 | ALDH1A1 (0.50) | TSHRALDH1A1SMN1; SMN2MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5560814-A | USE OF LOW CONCENTRATIONS FOR THE ELECTRODEPOSITION OF NICKEL ON STEEL OR BRASS SHAPES | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-01 | — | — | US | disclosed |