Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.51 |
| ▸ | HTR1A | P08908 | 7/20 | 0.50 |
| ▸ | HTR7 | P34969 | 7/20 | 0.50 |
| ▸ | HTR6 | P50406 | 7/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CTSG | P08311 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997644 | 0.89 | ELANE (0.47) | ELANEHTR1AHTR7HTR6NPSR1 | |
| SCHEMBL19923520 | 0.85 | ELANE (0.61) | ELANEHTR1AHTR7HTR6NPSR1 | |
| SCHEMBL8444410 | 0.83 | ELANE (0.49) | ELANEHTR1AHTR7HTR6NPSR1 | |
| SCHEMBL11475108 | 0.80 | ELANE (0.43) | ELANEHTR1AHTR7HTR6NPSR1 | |
| SCHEMBL8997578 | 0.80 | RAB9A (0.37) | — | |
| SCHEMBL8442425 | 0.75 | ELANE (0.45) | ELANEHTR1AHTR7HTR6NPSR1 | |
| SCHEMBL7449650 | 0.75 | CMA1 (0.56) | ELANEHTR1AHTR7HTR6NPSR1 | |
| SCHEMBL19923680 | 0.72 | ELANE (0.56) | ELANEHTR1AHTR7HTR6NPSR1 | |
| SCHEMBL11772829 | 0.70 | ELANE (0.68) | ELANENPSR1CTSGF2PLG | |
| SCHEMBL19923749 | 0.70 | NPSR1 (0.64) | ELANEHTR1AHTR7HTR6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572191-B1 | N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents | ROHM & HAAS (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5346913-A | Agricultural fungicides | ROHM AND HAAS COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0572191-A1 | N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents | ROHM AND HAAS COMPANY (US) | 1993-12-01 | — | — | EP | disclosed |