SCHEMBL19923680

SCHEMBL19923680

CC1(c2ccccc2)C(=O)N(Cc2ccccc2)C(=O)N1Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.56
NPSR1 Q6W5P4 1/20 0.54
CYP2C19 P33261 3/20 0.50
CTSG P08311 2/20 0.50
F2 P00734 1/20 0.50
PLG P00747 1/20 0.50
CMA1 P23946 1/20 0.50
CTRC Q99895 1/20 0.50
PRTN3 P24158 1/20 0.49
HTR1A P08908 3/20 0.44
HTR7 P34969 3/20 0.44
HTR6 P50406 3/20 0.44
GSK3A P49840 1/20 0.43
GSK3B P49841 1/20 0.43
MGLL Q99685 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6758440 0.87 ATM (0.46) ELANENPSR1CYP2C19CTSGPRTN3
SCHEMBL6758441 0.87 ATM (0.46) ELANENPSR1CYP2C19CTSGPRTN3
SCHEMBL4383512 0.87 ATM (0.46) ELANENPSR1CYP2C19CTSGPRTN3
SCHEMBL19923520 0.82 ELANE (0.61) ELANENPSR1CYP2C19CTSGF2
SCHEMBL19923635 0.81 ELANE (0.53) ELANENPSR1CYP2C19CTSGF2
SCHEMBL19923637 0.81 ELANE (0.44) ELANENPSR1CYP2C19CTSGF2
SCHEMBL6758456 0.80 ATM (0.43) ELANENPSR1CYP2C19CTSGPRTN3
SCHEMBL6758461 0.80 ATM (0.43) ELANENPSR1CYP2C19CTSGPRTN3
SCHEMBL6758466 0.80 ATM (0.43) ELANENPSR1CYP2C19CTSGPRTN3
SCHEMBL5645835 0.79 PLAU (0.45) F2PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN ELANE 1249/4885NPSR1 1322/4885CYP2C19 1347/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM ELANE 1276/4885NPSR1 1281/4885CYP2C19 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.