Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 12/20 | 0.50 |
| ▸ | MMP2 | P08253 | 8/20 | 0.49 |
| ▸ | MMP3 | P08254 | 7/20 | 0.49 |
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | CPA1 | P15085 | 2/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | MMP8 | P22894 | 4/20 | 0.48 |
| ▸ | MMP7 | P09237 | 3/20 | 0.48 |
| ▸ | FCER2 | P06734 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417820 | 0.89 | MME (0.61) | MMP1MMP2MMP3MMEACE | |
| SCHEMBL6413821 | 0.86 | MMP1 (0.55) | MMP1MMP2MMP3MMEMMP9 | |
| SCHEMBL6413824 | 0.86 | MMP1 (0.55) | MMP1MMP2MMP3MMEMMP9 | |
| SCHEMBL6416478 | 0.83 | MMP1 (0.64) | MMP1MMP2MMP3MMEMMP9 | |
| SCHEMBL6418586 | 0.81 | MME (0.61) | MMP1MMP2MMP3MMEACE | |
| SCHEMBL6413295 | 0.80 | MME (0.64) | MMP1MMP2MMP3MMEACE | |
| SCHEMBL7382794 | 0.80 | ACE (0.74) | MMEACECPA1ACE2 | |
| SCHEMBL6414037 | 0.80 | MME (0.74) | MMP1MMP2MMP3MMEACE | |
| SCHEMBL7895293 | 0.78 | MME (0.56) | MMP1MMP2MMP3MMEACE | |
| SCHEMBL7385849 | 0.77 | MMP1 (0.65) | MMP1MMP2MMP3MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728144-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEINASES | Chiroscience Limited (GB) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013289-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEINASES | CHIROSCIENCE LIMITED (GB) | 1995-05-18 | — | — | WO | claimed |
| EP-0728144-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEINASES | Chiroscience Limited (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013289-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEINASES | CHIROSCIENCE LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |