Terephthalic Acid

Terephthalic Acid

SCHEMBL8997649

O=C([O-])c1ccc(C(=O)[O-])cc1.[H+].[H+]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 18/20 0.68
CA1 P00915 17/20 0.68
CA4 P22748 1/20 0.63
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL7910695 0.97 CA2 (0.65) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL9930546 0.97 CA2 (0.65) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL9930111 0.97 CA2 (0.74) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL7897885 0.97 CA2 (0.74) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL2841686 0.93 CA2 (0.78) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL10900872 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL6665082 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL21958268 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL1535442 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL1006722 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3620830-B1 OPTICAL ELEMENT AND METHOD OF PRODUCING OPTICAL ELEMENT ARKRAY INC (JP) 2024-01-03 EP claimed
CN-107129429-A Carboxylate is the method and its purification process that organic ligand synthesizes the Cr of metal-organic framework materials MIL 101 南通职业大学 2017-09-05 CN claimed
CN-107075091-A Polymer from muconic acid isomers and its derivative 麦兰特公司 2017-08-18 CN claimed
CN-103804115-A Stabilizers for the stabilization of unsaturated hydrocarbon-based precursor AIR PROD & CHEM 2014-05-21 CN claimed
CN-101468937-A Stabilizers for stabilization of unsaturated hydrocarbon-based precursors AIR PROD & CHEM (US) 2009-07-01 CN claimed
CN-101389666-A Viscosity breaking process for olefin polymers CIBA HOLDING INC (CH) 2009-03-18 CN claimed
CN-100413820-C Nitroaromatic solubilizer for nitroxyls in aromatic solvents UNIROYAL CHEM CO INC (US) 2008-08-27 CN claimed
CN-101163736-A In-can stabilizer blend CIBA SC HOLDING AG (CH) 2008-04-16 CN claimed
CN-1230492-C Compositions and methods for inhibiting polymerization and polymer growth UNIROYAL CHEM CO INC (US) 2005-12-07 CN claimed
CN-1411499-A Composition and method for inhibiting polymerization and polymer growth UNIROYAL CHEM CO INC (US) 2003-04-16 CN claimed
CN-1064992-C Stabilizers for prevention of gum formation in gasoline CIBA SC HOLDING AG (CH) 2001-04-25 CN claimed
CN-1259114-A Polymerization inhibition of acrylates using blends of nitroxides CIBA SC HOLDING AG (CH) 2000-07-05 CN claimed
CN-1041513-C Inhibiting polymerization of vinyl aromatic monomers CIBA GEIGY AG (CH) 1999-01-06 CN claimed
CN-1172149-A Stabilizers for prevention of gum formation in gasoline CIBA SC HOLDING AG (CH) 1998-02-04 CN claimed
CN-1084155-A The resistance of vi-ny l aromatic monomers is poly- CIBA GEIGY AG (US) 1994-03-23 CN claimed
US-20260022473-A1 METHOD FOR PRODUCING A MONOMER FROM THE POLYMER COMPRISING THE MONOMER RHEINISCH-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN (DE) 2026-01-22 US disclosed
EP-4221503-B1 FUNGICIDAL COMPOSITIONS COMPRISING TRIALKYL SULFONIUM SALTS HELM AG (DE) 2025-08-20 EP disclosed
US-5198148-A Storage stability SHINKO ELECTRIC WORKS CO., LTD. (JP) 1993-03-30 US disclosed
US-4101669-A FUNGICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-07-18 US disclosed
US-4053612-A FUNGICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022473-A1 METHOD FOR PRODUCING A MONOMER FROM THE POLYMER COMPRISING THE MONOMER HAO2, PHGDH, APEH CA2 60/4885CA1 4/4885CA4 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.