Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997844 | 0.92 | PAOX (0.38) | HRH3PAOXSIGMAR1USP2ALDH1A1 | |
| SCHEMBL167231 | 0.85 | PAOX (0.47) | HRH3PAOXSIGMAR1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8950334 | 0.85 | HRH3 (0.48) | HRH3 | |
| Hydrochloric Acid SCHEMBL409216 | 0.83 | PAOX (0.45) | HRH3PAOXSIGMAR1MAPTUSP2 | |
| Hydrochloric Acid SCHEMBL374447 | 0.83 | PAOX (0.45) | HRH3PAOXSIGMAR1MAPTUSP2 | |
| SCHEMBL6798311 | 0.82 | CHKA (0.47) | HRH3PAOXSIGMAR1ALDH1A1 | |
| SCHEMBL7029723 | 0.81 | ALOX15 (0.46) | PAOXSIGMAR1MAPTUSP2ALDH1A1 | |
| SCHEMBL8997847 | 0.80 | MEN1 (0.52) | HRH3PAOXSIGMAR1MAPTUSP2 | |
| SCHEMBL25435212 | 0.80 | HRH3 (0.47) | HRH3PAOXSIGMAR1MAPTUSP2 | |
| SCHEMBL1782004 | 0.79 | PAOX (0.47) | PAOXSIGMAR1USP2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523303-A | ANTIULCER AND -SECRETORY AGENTS; GASTRIC H+K+ ATPASE INHIBITORS; NONTOXIC; OXIMES DERIVATIVES | EGIS GYOGYSZERGYAR RT. (HU) | 1996-06-04 | — | — | US | disclosed |
| EP-0619298-A2 | (Phenylmethylene)-2-(alkyl)-1- omega-(amino)-alkoxyimino -cycloalkane derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |