Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997893 | 0.94 | CCR3 (0.56) | MC4RSIGMAR1CCR3LMNAPOLB | |
| SCHEMBL10745029 | 0.84 | MC4R (0.65) | MC4RSIGMAR1CCR3LMNAPOLB | |
| SCHEMBL9096454 | 0.84 | SIGMAR1 (0.75) | MC4RSIGMAR1CCR3LMNAPOLB | |
| SCHEMBL27520452 | 0.83 | SIGMAR1 (0.46) | MC4RSIGMAR1LMNAPOLBHRH3 | |
| SCHEMBL8997724 | 0.82 | SIGMAR1 (0.46) | MC4RSIGMAR1CCR3LMNAPOLB | |
| Hydrochloric Acid SCHEMBL9703228 | 0.82 | SIGMAR1 (0.72) | MC4RSIGMAR1CCR3LMNAPOLB | |
| SCHEMBL6323999 | 0.81 | CCR3 (0.71) | MC4RSIGMAR1CCR3LMNAPOLB | |
| Hydrochloric Acid SCHEMBL10664920 | 0.79 | CCR3 (0.69) | MC4RSIGMAR1CCR3LMNAPOLB | |
| SCHEMBL9413496 | 0.78 | MC4R (0.77) | MC4RSIGMAR1CCR3LMNAPOLB | |
| SCHEMBL8997790 | 0.78 | SIGMAR1 (0.64) | MC4RSIGMAR1CCR3LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523303-A | ANTIULCER AND -SECRETORY AGENTS; GASTRIC H+K+ ATPASE INHIBITORS; NONTOXIC; OXIMES DERIVATIVES | EGIS GYOGYSZERGYAR RT. (HU) | 1996-06-04 | — | — | US | disclosed |
| EP-0619298-A2 | (Phenylmethylene)-2-(alkyl)-1- omega-(amino)-alkoxyimino -cycloalkane derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |