Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.60 |
| ▸ | MC4R | P32245 | 1/20 | 0.59 |
| ▸ | CCR3 | P51677 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096454 | 0.93 | SIGMAR1 (0.75) | SIGMAR1MC4RCCR3DRD4LMNA | |
| Hydrochloric Acid SCHEMBL9703228 | 0.91 | SIGMAR1 (0.72) | SIGMAR1MC4RCCR3DRD4LMNA | |
| SCHEMBL11141692 | 0.87 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RSLC6A3HRH4 | |
| SCHEMBL8327 | 0.87 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RSLC6A3HRH4 | |
| SCHEMBL11585348 | 0.87 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RSLC6A3HRH4 | |
| SCHEMBL688047 | 0.87 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RSLC6A3HRH4 | |
| SCHEMBL26532 | 0.87 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RSLC6A3HRH4 | |
| SCHEMBL3061933 | 0.85 | SIGMAR1 (0.75) | SIGMAR1HRH3MC4RCCR3SLC6A3 | |
| Hydrochloric Acid SCHEMBL4774633 | 0.85 | SIGMAR1 (0.74) | SIGMAR1HRH3MC4RHRH4DRD4 | |
| Bromide SCHEMBL10730905 | 0.85 | SIGMAR1 (0.74) | SIGMAR1HRH3MC4RSLC6A3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523303-A | ANTIULCER AND -SECRETORY AGENTS; GASTRIC H+K+ ATPASE INHIBITORS; NONTOXIC; OXIMES DERIVATIVES | EGIS GYOGYSZERGYAR RT. (HU) | 1996-06-04 | — | — | US | disclosed |
| EP-0619298-A2 | (Phenylmethylene)-2-(alkyl)-1- omega-(amino)-alkoxyimino -cycloalkane derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |