Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997826 | 1.00 | HRH3 (0.46) | HRH3SLC6A4SLC6A2 | |
| SCHEMBL8997944 | 0.98 | HRH3 (0.44) | HRH3SLC6A4 | |
| Hydrochloric Acid SCHEMBL8950232 | 0.88 | HRH3 (0.41) | HRH3 | |
| Hydrochloric Acid SCHEMBL8950284 | 0.88 | HRH3 (0.41) | HRH3 | |
| Hydrochloric Acid SCHEMBL8950352 | 0.86 | TP53 (0.39) | HRH3 | |
| Hydrochloric Acid SCHEMBL8950334 | 0.85 | HRH3 (0.48) | HRH3SLC6A4SLC6A2 | |
| SCHEMBL8997666 | 0.81 | KEAP1 (0.41) | HRH3 | |
| SCHEMBL7649376 | 0.81 | HRH3 (0.56) | HRH3SLC6A4 | |
| Hydrochloric Acid SCHEMBL27493872 | 0.80 | ALOX15 (0.42) | HRH3SLC6A4SLC6A2 | |
| SCHEMBL16312397 | 0.79 | HRH3 (0.61) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523303-A | ANTIULCER AND -SECRETORY AGENTS; GASTRIC H+K+ ATPASE INHIBITORS; NONTOXIC; OXIMES DERIVATIVES | EGIS GYOGYSZERGYAR RT. (HU) | 1996-06-04 | — | — | US | disclosed |
| EP-0619298-A2 | (Phenylmethylene)-2-(alkyl)-1- omega-(amino)-alkoxyimino -cycloalkane derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |