Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663809 | 0.83 | KMT2A (0.43) | LMNAL3MBTL1NSD2AKR1C3MAPT | |
| SCHEMBL28792769 | 0.80 | HTR7 (0.65) | LMNAL3MBTL1NSD2AKR1C3CNR2 | |
| SCHEMBL3393801 | 0.77 | HSD17B10 (0.46) | LMNAL3MBTL1NSD2AKR1C3MAPT | |
| SCHEMBL8997898 | 0.77 | MAPT (0.46) | LMNAL3MBTL1NSD2AKR1C3CNR2 | |
| SCHEMBL8663997 | 0.77 | KMT2A (0.46) | LMNAL3MBTL1NSD2AKR1C3MAPT | |
| SCHEMBL8667308 | 0.77 | MAPT (0.46) | LMNAL3MBTL1NSD2AKR1C3CNR2 | |
| SCHEMBL1450530 | 0.76 | AKR1C3 (0.68) | LMNAL3MBTL1NSD2AKR1C3CNR2 | |
| Ammonia Solution, Strong SCHEMBL28721079 | 0.74 | AKR1C3 (0.66) | LMNAL3MBTL1NSD2AKR1C3CNR2 | |
| SCHEMBL8666226 | 0.74 | NPC1 (0.41) | LMNAL3MBTL1NSD2CNR2MAPT | |
| SCHEMBL3543964 | 0.73 | LMNA (0.41) | LMNAL3MBTL1NSD2AKR1C3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574030-A | INHIBITING URINARY CONTRACTION, HETEROCYCLIC DIAMINES | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |