Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23408836 | 0.78 | CYP19A1 (0.39) | SLC7A5SLC1A3SLC1A2SLC1A1MAPK1 | |
| SCHEMBL8517612 | 0.77 | ALDH1A1 (0.36) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| SCHEMBL4762688 | 0.76 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| SCHEMBL7359844 | 0.76 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| SCHEMBL23408678 | 0.75 | SLC7A5 (0.43) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| SCHEMBL2368385 | 0.75 | NOS1 (0.39) | SLC7A5SLC1A3SLC1A2SLC1A1MAPK1 | |
| SCHEMBL29194171 | 0.75 | GSR (0.50) | MAPT | |
| SCHEMBL24414542 | 0.74 | MAPT (0.47) | MAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL24414476 | 0.74 | MAPT (0.47) | MAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL24414506 | 0.74 | MAPT (0.47) | MAPTTSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725636-A1 | HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE THESE IONS, COMPOSITIONS EMPLOYING THESE AGENTS, THERAPEUTIC METHODS FOR USING SUCH AGENTS AND PROCESSES FOR PREPARING THEM | FHJ SCIENTIFIC, INC. (US) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995010272-A1 | HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE THESE IONS, COMPOSITIONS EMPLOYING THESE AGENTS, THERAPEUTIC METHODS FOR USING SUCH AGENTS AND PROCESSES FOR PREPARING THEM | FHJ SCIENTIFIC, INC. (US) | 1995-04-20 | — | — | WO | disclosed |