SCHEMBL8998577

SCHEMBL8998577

CCCCCCc1ccc(C(=O)Cl)s1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 3/20 0.53
LMNA P02545 1/20 0.53
PRNP P04156 1/20 0.53
RECQL P46063 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
HPGD P15428 1/20 0.49
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
PTGER1 P34995 1/20 0.38
PTGER3 P43115 1/20 0.38
PTGER2 P43116 1/20 0.38
PTGDR Q13258 1/20 0.38
GPR35 Q9HC97 2/20 0.38
RARB P10826 4/20 0.37
MEN1 O00255 1/20 0.37
RARA P10276 1/20 0.37
MAPT P10636 1/20 0.37
MTOR P42345 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8998493 1.00 POLB (0.54) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL6653369 0.85 POLB (0.59) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL3176363 0.85 LMNA (0.71) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL8971725 0.85 POLB (0.59) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL8971941 0.85 POLB (0.59) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL25616720 0.83 POLB (0.66) POLBTDP1ALDH1A1LMNAPRNP
Hydrochloric Acid SCHEMBL8998499 0.83 POLB (0.57) POLBTDP1ALDH1A1LMNAPRNP
Hydrochloric Acid SCHEMBL8998584 0.83 POLB (0.57) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL26169734 0.83 POLB (0.57) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL846642 0.83 POLB (0.56) POLBTDP1ALDH1A1LMNAPRNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003411-A Preparation process of quinacridone derivative 淄博鸿润新材料有限公司 2023-04-25 CN disclosed
CN-116003411-A Preparation process of quinacridone derivative 淄博鸿润新材料有限公司 2023-04-25 CN disclosed
EP-0458347-B1 Liquid crystal composition and display device using same CANON KK (JP) 1996-09-11 EP disclosed
EP-0499252-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1996-09-11 EP disclosed
US-5413735-A Displays and visual aids CANON KABUSHIKI KAISHA (JP) 1995-05-09 US disclosed
EP-0500072-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1995-05-03 EP disclosed
US-5268123-A Structure containing thiophene and benzene rings CANON KABUSHIKI KAISHA (JP) 1993-12-07 US disclosed
US-5250218-A Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1993-10-05 US disclosed
EP-0364923-B1 MESOMORPHIC COMPOUND, LIQUID CRYSTAL COMPOSITION CONTAINING SAME AND LIQUID CRYSTAL DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 1993-07-28 EP disclosed
EP-0500072-A1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-08-26 EP disclosed
EP-0499252-A1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-08-19 EP disclosed
US-5116530-A Ferroelectrical optical apparatus containing thiophene groups CANON KABUSHIKI KAISHA (JP) 1992-05-26 US disclosed
EP-0458347-A2 Liquid crystal composition and display device using same CANON KABUSHIKI KAISHA (JP) 1991-11-27 EP disclosed
EP-0364923-A2 Mesomorphic compound, liquid crystal composition containing same and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-04-25 EP disclosed