SCHEMBL8998645

SCHEMBL8998645

O=C1c2ccc(S(=O)(=O)O)cc2C(=O)c2ccc(S(=O)(=O)O)cc21.[KH]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.48
▸ MAOA P21397 1/20 0.48
▸ UGT1A1 P22309 1/20 0.48
▸ MAOB P27338 1/20 0.48
▸ ESR2 Q92731 1/20 0.48
▸ PKM P14618 3/20 0.47
▸ ALDH1A1 P00352 5/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ MAPT P10636 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ HSD17B10 Q99714 2/20 0.45
▸ STAT3 P40763 1/20 0.45
▸ PKLR P30613 2/20 0.44
▸ PARG Q86W56 2/20 0.44
▸ APEX1 P27695 2/20 0.44
▸ LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517673 0.98 ESR1 (0.50) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL29445521 0.98 ESR1 (0.50) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL29600607 0.98 ESR1 (0.50) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL29490328 0.98 ESR1 (0.50) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL29561433 0.98 ESR1 (0.50) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL29352388 0.98 ESR1 (0.50) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL1782510 0.98 ESR1 (0.50) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL31059305 0.98 ESR1 (0.50) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL23357768 0.95 PKM (0.52) ESR1MAOAUGT1A1MAOBESR2
SCHEMBL2018087 0.95 ESR1 (0.48) ESR1MAOAUGT1A1MAOBESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12111315-B2 Smart glass slide for microarrays ROBERT BOSCH GMBH (DE) 2024-10-08 — — US claimed
EP-3779436-A2 METHODS FOR GENERATING PH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR MODULATING BIOMOLECULAR INTERACTIONS USING DOPAMINE HYDROCHLORIDE Robert Bosch GmbH (DE) 2021-02-17 — — EP claimed
US-4959753-A AN ELECTROLYTIC ELECTROCONDUCTIVE POLYMER DOPED WITH A NAPHTHALENE-OR ANTHRAQUINONESULFONATE ON A DIELECTRIC FILM FORMED FROM ANODIZING THE METAL SUBSTRATE; HEAT AND HUMIDITY RESISTANCE; SHELF LIFELEAK MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-09-25 — — US claimed
EP-0358239-A2 Solid electrolytic capacitor and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-03-14 — — EP claimed
EP-3708673-B1 METHOD AND DEVICE FOR ELECTRONICALLY CONTROLLING THE PH OF A SOLUTION BOSCH GMBH ROBERT (DE) 2025-03-26 — — EP disclosed
US-12111315-B2 Smart glass slide for microarrays ROBERT BOSCH GMBH (DE) 2024-10-08 — — US disclosed
US-11867660-B2 Electronic control of the pH of a solution close to an electrode surface ROBERT BOSCH GMBH (DE) 2024-01-09 — — US disclosed
CN-116685846-A Electronic control of the pH of a solution near the electrode surface 罗伯特·博世有限公司 2023-09-01 — — CN disclosed
US-11561198-B2 Electronic control of the pH of a solution close to an electrode surface ROBERT BOSCH GMBH (DE) 2023-01-24 — — US disclosed
US-10942146-B2 Electrochemically active agents for pH modulation in biological buffers ROBERT BOSCH GMBH (DE) 2021-03-09 — — US disclosed
EP-3320332-B1 METHODS FOR GENERATING PH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR BUBBLE DETECTION USING ELECTRODES BOSCH GMBH ROBERT (DE) 2021-03-03 — — EP disclosed
EP-3779436-A2 METHODS FOR GENERATING PH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR MODULATING BIOMOLECULAR INTERACTIONS USING DOPAMINE HYDROCHLORIDE Robert Bosch GmbH (DE) 2021-02-17 — — EP disclosed
CN-104428673-A Method for generating pH/ion concentration gradient near electrode surface to regulate biomolecule interaction BOSCH GMBH ROBERT 2015-03-18 — — CN disclosed
WO-2014151690-A1 DEVICE AND METHOD FOR ACCURATE PH MONITORING ON TRANSPARENT MICROARRAYS ROBERT BOSCH GMBH (DE) 2014-09-25 — — WO disclosed
US-20140274760-A1 SMART GLASS SLIDE FOR MICROARRAYS ROBERT BOSCH GMBH (DE) 2014-09-18 — — US disclosed
WO-2014008038-A1 METHODS FOR GENERATING PH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR MODULATING BIOMOLECULAR INTERACTIONS ROBERT BOSCH GMBH (DE) 2014-01-09 — — WO disclosed
EP-0358239-B1 Solid electrolytic capacitor and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1996-08-21 — — EP disclosed
EP-0617442-A2 Solid electrolytic capacitor and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1994-09-28 — — EP disclosed
US-4959753-A AN ELECTROLYTIC ELECTROCONDUCTIVE POLYMER DOPED WITH A NAPHTHALENE-OR ANTHRAQUINONESULFONATE ON A DIELECTRIC FILM FORMED FROM ANODIZING THE METAL SUBSTRATE; HEAT AND HUMIDITY RESISTANCE; SHELF LIFELEAK MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-09-25 — — US disclosed
EP-0358239-A2 Solid electrolytic capacitor and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-03-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10942146-B2 Electrochemically active agents for pH modulation in biological buffers CA2, PDE7A, CA1 ESR1 4041/4885MAOA 2029/4885UGT1A1 4562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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