Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684694 | 0.91 | ABCB1 (0.39) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL667409 | 0.91 | ABCB1 (0.39) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7479127 | 0.89 | ABCB1 (0.39) | ABCB1ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL29684755 | 0.88 | ABCB1 (0.38) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29786240 | 0.88 | ABCB1 (0.38) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL668085 | 0.88 | ABCB1 (0.38) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2684734 | 0.88 | ABCB1 (0.38) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8998876 | 0.85 | ABCB1 (0.57) | ABCB1CYP3A4 | |
| SCHEMBL12841128 | 0.82 | ABCB1 (0.36) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29685124 | 0.81 | ABCB1 (0.38) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |