Phenol

Phenol

SCHEMBL8998885

CCCc1ccc(O)cc1.Oc1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.57
ADRA2A P08913 3/20 0.57
SLC6A2 P23975 3/20 0.57
ADORA3 P0DMS8 2/20 0.57
TACR2 P21452 2/20 0.57
SLC6A4 P31645 2/20 0.57
SLC6A3 Q01959 2/20 0.57
KDM4E B2RXH2 2/20 0.57
ALDH1A1 P00352 2/20 0.57
LMNA P02545 1/20 0.57
SHBG P04278 1/20 0.57
TP53 P04637 1/20 0.57
CYP3A4 P08684 1/20 0.57
HSPD1 P10809 1/20 0.57
ADRB3 P13945 1/20 0.57
HTR2C P28335 1/20 0.57
HSPE1 P61604 1/20 0.57
HIF1A Q16665 1/20 0.57
TST Q16762 1/20 0.57
HSD17B10 Q99714 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL8320228 1.00 ESR1 (0.57) ESR1ADRA2ASLC6A2ADORA3TACR2
Phenol SCHEMBL25432652 0.93 OPRK1 (0.53) ESR1ADRA2ASLC6A2ADORA3TACR2
Phenol SCHEMBL28849322 0.93 OPRK1 (0.53) ESR1ADRA2ASLC6A2ADORA3TACR2
Biphenyl SCHEMBL27726761 0.91 MMP3 (0.56) ESR1ADRA2ASLC6A2ADORA3TACR2
Phenol SCHEMBL28200870 0.91 OPRK1 (0.51) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL52058 0.91 ESR1 (0.68) ESR1ADRA2ASLC6A2ADORA3TACR2
Toluene SCHEMBL27631478 0.90 ESR1 (0.52) ESR1ADRA2ASLC6A2ADORA3TACR2
Phenol SCHEMBL28189696 0.90 CNR2 (0.50) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL7522208 0.88 ESR1 (0.65) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL28362116 0.88 ESR1 (0.65) ESR1ADRA2ASLC6A2ADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100360488-C Bis (4-hydroxyaryl) alkanes BAYER AG (DE) 2008-01-09 CN claimed
CN-1411429-A Bis (4-hydroxyaryl) alkanes BAYER AG (DE) 2003-04-16 CN claimed
CN-102899049-A Novel double-halogenated vinyl ether liquid crystal compound and composition of novel double-halogenated vinyl ether liquid crystal compound and liquid crystal display JIANGSU HECHENG DISPLAY TECH 2013-01-30 CN disclosed
CN-100360488-C Bis (4-hydroxyaryl) alkanes BAYER AG (DE) 2008-01-09 CN disclosed
CN-1202059-C Bisphenol/phenol adducts BAYER AG (DE) 2005-05-18 CN disclosed
CN-1411429-A Bis (4-hydroxyaryl) alkanes BAYER AG (DE) 2003-04-16 CN disclosed
CN-1411430-A Bisphenol phenol adducts BAYER AG (DE) 2003-04-16 CN disclosed
EP-0612765-B1 Process for chlorination and chlorosulfonation of olefin polymers in the presence of fluorinated surfactants DU PONT (US) 1996-12-04 EP disclosed
EP-0608802-B1 Process for chlorination and chlorosulfonation of olefin polymers in suspensions of perfluorinated liquids DU PONT (US) 1996-09-04 EP disclosed
EP-0612765-A2 Process for chlorination and chlorosulfonation of olefin polymers in the presence of fluorinated surfactants E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-08-31 EP disclosed
EP-0608802-A2 Process for chlorination and chlorosulfonation of olefin polymers in suspensions of perfluorinated liquids E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-08-03 EP disclosed
US-5242988-A Process for chlorination and chlorosulfonation of olefin polymers in the presence of fluorinated surfactants E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-07 US disclosed
US-5242987-A Process for chlorination and chlorosulfonation of olefin polymers in suspensions of perfluorinated liquids E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-07 US disclosed