Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | KIF11 | P52732 | 9/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5189952 | 0.79 | KIF11 (0.47) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL9204405 | 0.78 | TSHR (0.46) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL9204391 | 0.78 | TSHR (0.46) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL16219565 | 0.76 | MEN1 (0.42) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL15306844 | 0.76 | MEN1 (0.42) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL14544187 | 0.74 | CYP2C9 (0.39) | ALDH1A1CYP2D6MEN1KMT2AKIF11 | |
| SCHEMBL2862802 | 0.73 | MEN1 (0.50) | ALDH1A1MEN1KMT2AKIF11SMN1; SMN2 | |
| SCHEMBL11475050 | 0.73 | CYP19A1 (0.57) | ALDH1A1MEN1KMT2AKIF11SMN1; SMN2 | |
| SCHEMBL7768882 | 0.73 | MEN1 (0.50) | ALDH1A1MEN1KMT2AKIF11SMN1; SMN2 | |
| SCHEMBL813126 | 0.73 | CYP19A1 (0.57) | ALDH1A1MEN1KMT2AKIF11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554624-A | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS | J. URIACH & CIA. (ES) | 1996-09-10 | — | — | US | disclosed |
| EP-0669333-A1 | New imidazopyridine derivatives as angiotensin II antagonists | J. URIACH & CIA. S.A. (ES) | 1995-08-30 | — | — | EP | disclosed |