SCHEMBL7768882

SCHEMBL7768882

Cc1ccc(C(O)(c2ccccc2)C(O)(c2ccccc2)c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
TSHR P16473 2/20 0.48
LMNA P02545 2/20 0.48
ALOX12 P18054 1/20 0.48
ACHE P22303 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
MAPK1 P28482 2/20 0.47
XBP1 P17861 1/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KIF11 P52732 7/20 0.47
CYP19A1 P11511 2/20 0.44
ALDH1A1 P00352 2/20 0.44
POLB P06746 1/20 0.44
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
CYP3A4 P08684 2/20 0.43
CES2 O00748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2862802 1.00 MEN1 (0.50) MEN1KMT2ATSHRLMNAALOX12
SCHEMBL7763633 0.89 TSHR (0.55) MEN1KMT2ATSHRLMNAACHE
SCHEMBL2858670 0.89 CYP2C9 (0.50) MEN1KMT2ATSHRLMNAALOX12
SCHEMBL15106961 0.89 TSHR (0.46) MEN1KMT2ATSHRLMNAALOX12
SCHEMBL5865830 0.87 NR1H2 (0.51) MEN1KMT2ATSHRLMNAALOX12
SCHEMBL11475050 0.85 CYP19A1 (0.57) MEN1KMT2ATSHRLMNAALOX12
SCHEMBL813126 0.85 CYP19A1 (0.57) MEN1KMT2ATSHRLMNAALOX12
SCHEMBL7173455 0.84 CYP1A2 (0.48) MEN1KMT2ATSHRLMNASMN1; SMN2
SCHEMBL36629 0.84 CYP1A2 (0.48) MEN1KMT2ATSHRLMNASMN1; SMN2
SCHEMBL4457147 0.83 MEN1 (0.50) MEN1KMT2ATSHRLMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4106938-A VESICULATING AGENT WHICH LIBERATES GAS ON EXPOSURE TO ACTIVATING RADIATION, THERMOPLASTIC BINDER, DIOL SPEED-INCREASING AGENT EASTMAN KODAK COMPANY (US) 1978-08-15 US claimed
CN-114907196-B Method for preparing carbonyl compound by aryl substituted o-diol oxidative cleavage 赣南医学院 2024-01-05 CN disclosed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 US disclosed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US disclosed
EP-0800116-B1 Photoresist composition MITSUBISHI CHEM CORP (JP) 2001-08-22 EP disclosed
US-5759736-A Photoresist composition MITSUBISHI CHEMICAL CORPORATION (JP) 1998-06-02 US disclosed
EP-0800116-A1 Photoresist composition Mitsubishi Chemical Corporation (JP) 1997-10-08 EP disclosed
US-4106938-A VESICULATING AGENT WHICH LIBERATES GAS ON EXPOSURE TO ACTIVATING RADIATION, THERMOPLASTIC BINDER, DIOL SPEED-INCREASING AGENT EASTMAN KODAK COMPANY (US) 1978-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 MEN1 1056/4885KMT2A 3974/4885TSHR 1973/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 MEN1 1056/4885KMT2A 3974/4885TSHR 1973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.