Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998904 | 1.00 | LMNA (0.57) | LMNAALDH1A1MAPK1CYP19A1MAPT | |
| Etocrylene SCHEMBL1768864 | 0.94 | ALDH1A1 (0.62) | LMNAALDH1A1MAPK1CYP19A1MAPT | |
| Etocrylene SCHEMBL39390 | 0.94 | ALDH1A1 (0.62) | LMNAALDH1A1MAPK1CYP19A1MAPT | |
| SCHEMBL5711693 | 0.94 | ALDH1A1 (0.49) | LMNAALDH1A1MAPK1MAPTRAB9A | |
| Etocrylene SCHEMBL4076085 | 0.93 | ALDH1A1 (0.61) | LMNAALDH1A1MAPK1CYP19A1MAPT | |
| SCHEMBL12832324 | 0.90 | ALDH1A1 (0.56) | LMNAALDH1A1MAPK1CYP19A1MAPT | |
| SCHEMBL14451735 | 0.89 | ALDH1A1 (0.55) | LMNAALDH1A1MAPK1CYP19A1MAPT | |
| Etocrylene SCHEMBL9180144 | 0.89 | ALDH1A1 (0.67) | LMNAALDH1A1MAPK1CYP19A1MAPT | |
| SCHEMBL12758735 | 0.88 | LMNA (0.54) | LMNAALDH1A1MAPK1CYP19A1MAPT | |
| SCHEMBL1998828 | 0.88 | CYP19A1 (0.56) | LMNAALDH1A1MAPK1CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554624-A | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS | J. URIACH & CIA. (ES) | 1996-09-10 | — | — | US | disclosed |
| EP-0669333-A1 | New imidazopyridine derivatives as angiotensin II antagonists | J. URIACH & CIA. S.A. (ES) | 1995-08-30 | — | — | EP | disclosed |