Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 7/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | PTPRB | P23467 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691089 | 0.86 | MMP8 (0.56) | MMP8PTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL6117630 | 0.85 | MMP8 (0.56) | MMP8PTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL28354143 | 0.84 | PTPRB (0.49) | PTPRBSMN1; SMN2RECQLCYP3A4ALDH1A1 | |
| SCHEMBL27559394 | 0.82 | SMN1; SMN2 (0.55) | MMP8SMN1; SMN2HIF1ARECQLCYP3A4 | |
| SCHEMBL8215905 | 0.82 | SMN1; SMN2 (0.55) | MMP8SMN1; SMN2HIF1ARECQLCYP3A4 | |
| Ammonia Solution, Strong SCHEMBL29079452 | 0.81 | MMP8 (0.51) | MMP8PTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL20241701 | 0.80 | SMN1; SMN2 (0.58) | MMP8PTPN2PTPN1PTPRAPTPRB | |
| Carbamic Acid SCHEMBL27809934 | 0.80 | PTPRB (0.47) | MMP8PTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL20241700 | 0.80 | SMN1; SMN2 (0.58) | MMP8PTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL8745476 | 0.79 | SLC6A2 (0.52) | MMP8PTPN2PTPN1PTPRAPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6256278-A | — | — | None | — | — | JP | disclosed |
| US-5556874-A | ENZYME INHIBITORS AS ANTICARCINOGENIC AGENTS | WARNER LAMBERT COMPANY (US) | 1996-09-17 | — | — | US | disclosed |
| US-5464861-A | Anticarcinogenic agents | WARNER-LAMBERT (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0654024-A1 | 2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1995-05-24 | — | — | EP | disclosed |
| JP-H06256278-A | OPTICALLY ACTIVE ALPHA-CARBAMOYLALKANOIC ACID DERIVATIVE AND ITS PRODUCTION | NISSAN CHEM IND LTD | 1994-09-13 | — | — | JP | disclosed |
| WO-1994003427-A1 | 2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1994-02-17 | — | — | WO | disclosed |