Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826090 | 0.80 | PDPK1 (0.44) | PTPN1GSK3BCES1CES2PDPK1 | |
| SCHEMBL8948923 | 0.78 | HTT (0.40) | KDM4EHPGDAKR1C3FOLH1ALOX15 | |
| SCHEMBL3093625 | 0.77 | AKR1C3 (0.55) | PTPN1GSK3BCES1CES2MAPT | |
| SCHEMBL8999341 | 0.76 | CES2 (0.65) | PTPN1GSK3BCES1CES2PDPK1 | |
| SCHEMBL7955212 | 0.75 | ALDH1A1 (0.38) | CES1CES2PDPK1KDM4ETSHR | |
| SCHEMBL27296890 | 0.75 | PDE4A (0.45) | PTPN1GSK3BCES1CES2 | |
| SCHEMBL63954 | 0.75 | CES1 (0.50) | CES1CES2KDM4ECYP3A4MAPT | |
| SCHEMBL3978126 | 0.75 | CES2 (0.58) | PTPN1GSK3BCES1CES2MAPT | |
| SCHEMBL8948909 | 0.74 | ALDH1A1 (0.43) | KDM4EHPGDSMN1; SMN2TSHRKMT2A | |
| SCHEMBL8948905 | 0.74 | ALDH1A1 (0.43) | KDM4EHPGDSMN1; SMN2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554624-A | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS | J. URIACH & CIA. (ES) | 1996-09-10 | — | — | US | disclosed |
| EP-0669333-A1 | New imidazopyridine derivatives as angiotensin II antagonists | J. URIACH & CIA. S.A. (ES) | 1995-08-30 | — | — | EP | disclosed |