Methane

Methane

SCHEMBL8999429

C.Cc1ccc(NC(O)=S)cc1.NC(O)=S.[NaH]

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
HPGD P15428 1/20 0.52
KIF11 P52732 1/20 0.48
MEN1 O00255 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C19 P33261 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
GRIN3A Q8TCU5 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
TDP1 Q9NUW8 3/20 0.45
ALDH1A1 P00352 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11782099 0.94 NPC1 (0.53) NPC1RAB9AHPGDKIF11MEN1
SCHEMBL7213273 0.89 NPC1 (0.61) NPC1RAB9AHPGDMEN1CYP1A2
Methane SCHEMBL9753979 0.81 ALDH1A1 (0.64) NPC1RAB9AMEN1CYP3A4KMT2A
Methane SCHEMBL1286316 0.79 ALDH1A1 (0.67) NPC1RAB9AMEN1CYP3A4KMT2A
SCHEMBL1278440 0.79 ALDH1A1 (0.61) NPC1RAB9AHPGDKIF11MEN1
Methane SCHEMBL9770392 0.78 CYP1A2 (0.69) NPC1HPGDMEN1CYP1A2CYP3A4
Methane SCHEMBL11774994 0.77 ALDH1A1 (0.64) NPC1RAB9AMEN1CYP3A4KMT2A
SCHEMBL10882395 0.77 ALDH1A1 (0.59) NPC1RAB9AHPGDKIF11MEN1
Ethane SCHEMBL3723781 0.77 TAS2R38 (0.64) NPC1RAB9AHPGDMEN1CYP1A2
SCHEMBL9725052 0.77 KMT2A (0.53) NPC1RAB9AHPGDKIF11MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5506263-A Benzyl derivatives and pesticides containing them BASF AKTIENGESELLSCHAFT (DE) 1996-04-09 US disclosed
US-5416110-A Benzyl derivatives and pesticides containing them BASF AKTIENGESELLSCHAFT (DE) 1995-05-16 US disclosed