SCHEMBL8999616

SCHEMBL8999616

Cc1cc(O)c(C(C)C)cc1Oc1cc(C(C)C)c(O)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.57
TRPA1 O75762 1/20 0.45
CHRM1 P11229 1/20 0.45
SLC6A2 P23975 1/20 0.45
ADRA1A P35348 1/20 0.45
HTR2B P41595 1/20 0.45
PKM P14618 3/20 0.44
CYP1A2 P05177 3/20 0.42
CYP2D6 P10635 3/20 0.42
MAPK1 P28482 1/20 0.42
MAPT P10636 5/20 0.41
KMT2A Q03164 4/20 0.41
ALOX15 P16050 3/20 0.41
THRB P10828 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
HIF1A Q16665 2/20 0.41
G6PD P11413 2/20 0.40
ALDH1A1 P00352 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11797170 0.87 LMNA (0.56) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL1494397 0.86 LMNA (0.55) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL28323422 0.84 LMNA (0.53) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL16736804 0.84 LMNA (0.53) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL28228776 0.82 LMNA (0.52) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL16736742 0.81 LMNA (0.55) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL214157 0.80 LMNA (0.68) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL29872559 0.80 LMNA (0.68) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL11388884 0.80 LMNA (0.49) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL10616596 0.80 LMNA (0.49) LMNATRPA1CHRM1SLC6A2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0518241-B1 Hydroformylation process and bisphosphite compound used therein MITSUBISHI CHEM CORP (JP) 1996-09-11 EP disclosed
US-5391801-A Used to form respective aldehyde by reacting olefinic compound with carbon monoxide and hydrogen in presence of group 8 metal catalyst MITSUBISHI KASEI CORPORATION (JP) 1995-02-21 US disclosed
US-5235113-A Reacting olefin with hydrogen and carbon monoxide in the presence of a group 8 metal catalyst and a phosphite compound MITSUBISHI KASEI CORPORATION (JP) 1993-08-10 US disclosed
EP-0518241-A2 Hydroformylation process and bisphosphite compound used therein Mitsubishi Chemical Corporation (JP) 1992-12-16 EP disclosed
EP-0042622-B1 Spiro[2,2,6,6-tetramethyl-piperidine-4,2'-(1',3'-dioxo(ol)an]-derivatives and stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-08-19 EP disclosed
EP-0022997-B1 2,2,6,6-TETRAMETHYL-4-PIPERIDYL CARBOXYLIC ACID ESTERS AND AMIDES OF MONO AND POLY ALCOHOLS, PHENOLS AND AMINES AND SYNTHETIC POLYMER COMPOSITIONS STABILIZED THEREBY ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1985-10-02 EP disclosed
EP-0045358-B1 2,2,6,6-TETRAMETHYL-4-PIPERIDYL SPIRO ALIPHATIC ETHERS AS STABILIZERS FOR SYNTHETIC POLYMERS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1985-08-14 EP disclosed
EP-0016986-B1 HEAT STABILIZED POLYMERIC COMPOSITION CONTAINING AN OLEFIN POLYMER OR COPOLYMER AND METHOD FOR ENHANCING THE THERMAL STABILITY OF COMPOSITIONS CONTAINING SUCH POLYMERS, INORGANIC FILLERS AND CONVENTIONAL STABILIZERS R.T. VANDERBILT COMPANY, INC. (US) 1984-05-16 EP disclosed
US-4405736-A 2,2,6,6-Tetramethyl-4-piperidyl spiro aliphatic ethers and stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-09-20 US disclosed
US-4396735-A N-HETEROCYCLIC COMPOUND AND A HETEROCYCLIC ACID HYDRAZIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-08-02 US disclosed
US-4199495-A Thiolcarbonate ester stabilizers ARGUS CHEMICAL CORP. (US) 1980-04-22 US disclosed
US-4178280-A Stabilized polyolefin composition R. T. VANDERBILT COMPANY, INC. (US) 1979-12-11 US disclosed
US-4174297-A Polyhydric phenol coester stabilizers ARGUS CHEMICAL CORPORATION (US) 1979-11-13 US disclosed
US-4171298-A SUBSTITUTED ORTHO-ALKYLHYDROXYBENZYLPROPANE-1,3-DIOL ESTERS ARGUS CHEMICAL CORPORATION (US) 1979-10-16 US disclosed
US-4146517-A FOR SYNTHETIC RESINS AGAINST HEAT ARGUS CHEMICAL CORPORATION (US) 1979-03-27 US disclosed
US-4145333-A POLYPHOSPHONATES OR PHOSPHONATE COMPOUNDS ARGUS CHEMICAL CORPORATION (US) 1979-03-20 US disclosed
US-4115476-A 2,2,6,6-Tetramethyl-4-piperidyl carbonic acid esters of dihydric alcohols and phenols as stabilizers for synthetic polymers ARGUS CHEMICAL CORPORATION (US) 1978-09-19 US disclosed
US-4107136-A Synthetic resin stabilizer comprising an organic phosphite and a carbonate ARGUS CHEMICAL CORPORATION (US) 1978-08-15 US disclosed
US-4105629-A SYNTHETIC RESIN STABILIZER COMPRISING A THIOETHER ESTER AND HINDERED PHENOLIC CARBONATE ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4100132-A RESISTANCE TO METAL-CATALYZED OXIDATIVE DEGRADATION R. T. VANDERBILT COMPANY, INC. (US) 1978-07-11 US disclosed