Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999616 | 0.87 | LMNA (0.57) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL29640497 | 0.83 | LMNA (0.54) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL11043528 | 0.83 | LMNA (0.54) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL31545975 | 0.78 | LMNA (0.56) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL21095165 | 0.78 | LMNA (0.56) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| Thymol SCHEMBL429156 | 0.76 | TRPA1 (0.72) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL1494397 | 0.74 | LMNA (0.55) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL29087264 | 0.74 | HTR2A (0.51) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL6149689 | 0.74 | LMNA (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| Thymol SCHEMBL22165 | 0.73 | LMNA (1.00) | LMNATRPA1CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966779-A | SYMPATHOLYTIC | WARNER-LAMBERT COMPANY (US) | 1976-06-29 | — | — | US | disclosed |