Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266317 | 0.79 | CA12 (0.70) | ARSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL2004893 | 0.79 | AR (0.64) | ARSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL10186908 | 0.78 | MEN1 (0.75) | ALDH1A1ARSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL874437 | 0.78 | AR (0.62) | ARSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL4667240 | 0.78 | PTPN1 (0.61) | ALDH1A1ARSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL339813 | 0.78 | LMNA (0.82) | SMN1; SMN2RAB9ACA12CA1CA2 | |
| SCHEMBL27367676 | 0.78 | LMNA (0.82) | SMN1; SMN2RAB9ACA12CA1CA2 | |
| SCHEMBL11268094 | 0.76 | NOX1 (0.74) | SMN1; SMN2RAB9ALMNACYP1A2PTGS1 | |
| SCHEMBL11548098 | 0.76 | MAOB (0.59) | ARSMN1; SMN2RAB9ACA12CA1 | |
| Benzylphenylether SCHEMBL8999674 | 0.76 | AR (0.69) | ALDH1A1ARSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484780-A | CARDIOVASCULAR, HYPOTENSIVE | ELI LILLY AND COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| US-5401851-A | Preparation of proline derivatives | ELI LILLY AND COMPANY (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0573271-A1 | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1993-12-08 | — | — | EP | disclosed |