Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004893 | 0.84 | AR (0.64) | SMN1; SMN2LMNAPTGS1PTGS2PPARG | |
| SCHEMBL4668653 | 0.83 | PTPN1 (0.44) | PTPN1ALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL5184334 | 0.78 | LMNA (0.69) | ALDH1A1SMN1; SMN2LMNAALOX5PTGS1 | |
| SCHEMBL8999638 | 0.78 | ALDH1A1 (0.63) | PTPN1ALDH1A1SMN1; SMN2LMNAALOX5 | |
| SCHEMBL6735454 | 0.78 | GRM2 (0.71) | PTPN1ALDH1A1SMN1; SMN2LMNAGRM2 | |
| SCHEMBL5184339 | 0.78 | KMT2A (0.61) | SMN1; SMN2LMNAALOX5PTGS1PTGS2 | |
| SCHEMBL874437 | 0.76 | AR (0.62) | SMN1; SMN2LMNAALOX5PTGS1PTGS2 | |
| SCHEMBL4773148 | 0.76 | ALDH1A1 (0.56) | PTPN1ALDH1A1SMN1; SMN2LMNAGRM2 | |
| SCHEMBL10561547 | 0.76 | GRM2 (0.60) | SMN1; SMN2LMNAGRM2 | |
| SCHEMBL12808838 | 0.76 | ALDH1A1 (0.60) | PTPN1ALDH1A1SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |