Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493006 | 0.93 | TSHR (0.41) | ACHETSHRCHRM2MAPTHTT | |
| SCHEMBL28050019 | 0.92 | P2RX7 (0.37) | ACHETSHRHTTALDH1A1 | |
| SCHEMBL28049977 | 0.92 | P2RX7 (0.37) | ACHETSHRHTTALDH1A1 | |
| SCHEMBL9441833 | 0.88 | TSHR (0.45) | ACHETSHRMAPTHTTALDH1A1 | |
| SCHEMBL27534154 | 0.87 | TSHR (0.36) | ACHETSHRMAPTHTTALDH1A1 | |
| SCHEMBL7558656 | 0.82 | ACHE (0.39) | ACHETSHRMAPTHTTALDH1A1 | |
| SCHEMBL28045144 | 0.77 | CNR1 (0.37) | HTTALDH1A1 | |
| SCHEMBL28045054 | 0.77 | CNR1 (0.37) | HTTALDH1A1 | |
| SCHEMBL7563201 | 0.76 | TSHR (0.43) | ACHETSHRMAPTHTTALDH1A1 | |
| SCHEMBL28227589 | 0.74 | TLR8 (0.35) | TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341773-B1 | Process for the preparation of lactones | SHELL INT RESEARCH (NL) | 1996-09-11 | — | — | EP | disclosed |
| EP-0293053-B1 | PROCESS FOR THE PREPARATION OF CYCLIC CARBOXYLIC ANHYDRIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-04 | — | — | EP | disclosed |
| US-4960906-A | Process for the preparation of lactones from higher alkenols | SHELL OIL COMPANY (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0341773-A1 | Process for the preparation of lactones | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-11-15 | — | — | EP | disclosed |
| US-4849542-A | Process for the preparation of oxo-alkanedioic acids or diesters thereof | SHELL OIL COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0293053-A2 | Process for the preparation of cyclic carboxylic anhydrides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-11-30 | — | — | EP | disclosed |