Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.34 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24233010 | 0.85 | CES2 (0.41) | CES2KDM4ES1PR1S1PR3KIF11 | |
| SCHEMBL11109288 | 0.84 | S1PR1 (0.36) | CES2KDM4ES1PR1S1PR3GPR35 | |
| SCHEMBL30744551 | 0.84 | HSP90AA1 (0.39) | CES2KDM4ES1PR1S1PR3 | |
| SCHEMBL609557 | 0.84 | HSP90AA1 (0.39) | CES2KDM4ES1PR1S1PR3 | |
| SCHEMBL11104202 | 0.84 | S1PR1 (0.38) | CES2KDM4ES1PR1S1PR3KIF11 | |
| SCHEMBL20350885 | 0.84 | KDM4E (0.36) | CES2KDM4ES1PR1S1PR3KIF11 | |
| SCHEMBL18711831 | 0.79 | CYP3A4 (0.43) | CES2KDM4ES1PR1S1PR3 | |
| SCHEMBL4018885 | 0.79 | CES2 (0.36) | CES2KDM4ES1PR1S1PR3GPR84 | |
| SCHEMBL4021804 | 0.77 | PDE2A (0.39) | CES2KDM4ES1PR1S1PR3 | |
| SCHEMBL31481281 | 0.76 | ALDH1A1 (0.44) | KDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206482-B | Synthesis method of 4-trifluoromethyl nicotinamide | 山东京博生物科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-118206482-A | Synthesis method of 4-trifluoromethyl nicotinamide | 山东京博生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-5578697-A | DIELECTRIC POLYMERS FOR ELECTRONICS | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-11-26 | — | — | US | disclosed |