Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CPT2 | P23786 | 1/20 | 0.46 |
| ▸ | CPT1A | P50416 | 1/20 | 0.46 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL3172731 | 0.96 | MEN1 (0.50) | MEN1KMT2AFAAHMAPK1CPT2 | |
| SCHEMBL3166335 | 0.93 | FAAH (0.59) | MEN1KMT2AFAAHMAPK1CPT2 | |
| SCHEMBL11274282 | 0.89 | FAAH (0.51) | MEN1KMT2AFAAHMAPK1CPT2 | |
| SCHEMBL11363461 | 0.89 | FAAH (0.51) | MEN1KMT2AFAAHMAPK1CPT2 | |
| Phosphoric Acid SCHEMBL10489010 | 0.82 | FAAH (0.57) | MEN1KMT2AFAAHMAPK1CPT2 | |
| SCHEMBL12435848 | 0.77 | FAAH (0.67) | MEN1KMT2AFAAHMAPK1PLA2G10 | |
| SCHEMBL12435872 | 0.77 | FAAH (0.67) | MEN1KMT2AFAAHMAPK1PLA2G10 | |
| SCHEMBL1310123 | 0.74 | CPT2 (0.51) | MEN1KMT2AFAAHMAPK1CPT2 | |
| SCHEMBL118838 | 0.74 | CPT2 (0.51) | MEN1KMT2AFAAHMAPK1CPT2 | |
| SCHEMBL339771 | 0.74 | CPT2 (0.51) | MEN1KMT2AFAAHMAPK1CPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653974-B1 | METHOD OF MAKING A COATED ABRASIVE ARTICLE CONTAINING A CONDUCTIVE BACKING | MINNESOTA MINING & MFG (US) | 1996-09-18 | — | — | EP | disclosed |