⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11663807 | 0.75 | — | — | |
| SCHEMBL5704883 | 0.75 | — | — | |
| SCHEMBL30983 | 0.67 | — | — | |
| SCHEMBL8161711 | 0.67 | — | — | |
| SCHEMBL4812801 | 0.65 | — | — | |
| SCHEMBL5327502 | 0.65 | — | — | |
| SCHEMBL3409575 | 0.63 | — | — | |
| SCHEMBL5141358 | 0.63 | — | — | |
| SCHEMBL1326815 | 0.61 | ALDH1A1 (0.36) | — | |
| SCHEMBL11666964 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506628-B1 | Aminoacyl and oligopeptidyl derivatives of allopurinol exhibiting immunostimulatory activity, and pharmaceutical formulations containing these substances | SIGMA TAU IND FARMACEUTI (IT) | 1996-09-18 | — | — | EP | disclosed |
| US-5272151-A | Aminoacyl and oligopeptidyl derivatives of allopurinol exhibiting immunostimulatory activity, and pharmaceutical formulations containing these substances | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1993-12-21 | — | — | US | disclosed |
| EP-0506628-A2 | Aminoacyl and oligopeptidyl derivatives of allopurinol exhibiting immunostimulatory activity, and pharmaceutical formulations containing these substances | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1992-09-30 | — | — | EP | disclosed |